I want to measure molecular weight or study light scattering.

The molecular weight of biological materials and polymers can be determined from both static and dynamic light scattering experiments using the Zetasizer Nano. In addition the molecular size of very small molecules in solution can be measured using the Malvern Zetasizer Nano.

I want to measure:

	Molecular weight measurement using dynamic light scattering experiments: The Zetasizer Nano S and Nano ZS can be used to measure the size of molecules, and this is then interpreted as a molecular weight distribution. The calculation uses the Mark-Houwinck equations. These rely on a calibration technique where examples of the same material of known molecular weight are available. These are used to recalculate the size axis from a size distribution experiment in terms of molecular weight. Sizes can be measured of molecules greater than 1,000 Da.
	Molecular weight measurement using a single angle spectrometer: The Malvern Zetasizer Nano S and ZS has been designed to use the intensity of light scattered at a single angle over a range of sample concentrations to determine absolute molecular weight. This technique is applicable to globular polymers such as proteins up to 19,000kDa and random coil polymers up to 500kDa.
	Molecular size measurement using dynamic light scattering: The Malvern Zetasizer Nano S uses dynamic light scattering to measure size, and is sensitive enough to measure the size of molecules below 1000 Da. The molecular size measurement does not require prior knowledge of the material dn/dc value, and can also provide size distributions, which may be important for the determination of aggregates.