Particle size analysis, zeta potential measurement, and molecular weight measurement are three of the most important parameters for the colloid and polymer chemist
Zetasizer range

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Malvern Instruments - Zetasizer

  Take a look at the Zetasizer systems features to find out which is best to meet your needs.

Malvern Instruments’ Zetasizer range uses light scattering techniques to measure hydrodynamic size, zeta potential and molecular weight of proteins and nanoparticles.

Technology – Unequalled sensitivity and versatility are achieved using the latest technology:

  • Patented NIBS optics improves sensitivity and size range /concentration range in the Zetasizer Nano S and ZS
  • M3-PALS is the leading technology for measurement of Zeta-potential.
  • Single-mode fibre, 50 m W laser and focused optics enable measurements of unrivalled quality of Proteins and other biomolecules.
  • Zetasizer µV as a light scattering detector for SEC

Applications:

  • Colloids – Measure the size and zeta-potential to optimise stability and shelf life and speed up formulation development.  Automate pH titrations and measurements using the optional autotitrator.
  • Nanoparticles – Measure size, polydispersity and zeta-potential to optimise production processes.
  • Proteins – Determine the presence of aggregates; screen for optimum crystallisation conditions; and study oligomer formation in as little as 2μL of sample, requiring just nanograms of material.
  • Proteins by SEC-LS – Measure absolute molecular weight, absolute size, oligomerisation state, aggregate formation and sample polydispersity, conjugate composition and second virial coefficient.

 

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Systems:

 
Zetasizer Nano		  
Zetasizer Nano - The ultimate versatile system
Characterise the size, distribution, zeta potential and molecular weight of colloids, nanoparticles and biomolecules. Automate changes in conditions such as pH and conductivity using the optional autotitrator.
Zetasizer Nano
 
Zetasizer APS		  
Zetasizer APS - DLS Plate Sampling Technology for unparalleled data quality and automation
A robust, simple to operate, Dynamic Light Scattering system that automates measurements from samples in industry standard 96- or 384-well plates to add the power of advanced light scattering analysis to your laboratory.
Zetasizer APS
 
Zetasizer Micro V		  
Zetasizer µV - Zetasizer V - Dedicated to the size and MW measurement of proteins
Measure as low a volume as 2µL. Combined with the ultimate sensitivity, this enables the measurement of 40 picograms of a 66kDa protein.
Zetasizer Micro V